Category Article

Chapter 3 of Strategies and Tactics in Organic Synthesis on our synthetic work on PKS-NRPS metabolites

Read this STOS chaper on our Bioinspired Adventures in the Total Synthesis of Mixed Polyketide–Nonribosomal Peptide Natural Products B. Nay,* M. Zaghouani, B. Laroche, S. Prévost, X.-W. Li, A. Ear, N. Riache in Strategies and Tactics in Organic Synthesis, Vol. 13 (2017), M. Harmata (Ed.), Advertisements

Fungal sesquiterpenes with special reactivity in Organic Letters

Just released A reactive eremophilane and its antibacterial 2(1H)‑naphthalenone rearrangement product, witnesses of a microbial chemical warfare S. Amand, M. Vallet, L. Guedon, G. Genta-Jouve, F. Wien, S. Mann, J. Dupont, S. Prado* and B. Nay* Organic Letters 2017, in press, doi: 10.1021/acs.orglett.7b01788 Abstract: Two sesquiterpenes, 4-epi-microsphaeropsisin (1) and a dihydrofurano-2(1H)-naphthalenone (variabilone, 2) which represents […]

New paper from Chinese collaboration

Asymmetric Total Synthesis of Distaminolyne A and Revision of its Absolute Configuration D.-Y. Sun, G.-Y. Han, J.-X. Gong, B. Nay, X.-W. Li,* Y.-W. Guo* Organic Letters 2017, in press, doi: 10.1021/acs.orglett.6b03892 Abstract: The first total synthesis of a marine derived polyacetylene, distaminolyne A, and its enantiomer were achieved from the commercially available undec-10-en-1-ol. A key […]

Our first paper on toxic butterflies and mimicry, featuring Aimilia’s work!

Variation in cyanogenic compounds concentration within a Heliconius butterfly community: does mimicry explain everything? M. Arias,* A. Meichanetzoglou, M. Elias, N. Rosser, D. L. de-Silva, B. Nay, V. Llaurens BMC Evolutionary Biology2016, 16, 272, doi: 10.1186/s12862-016-0843-5

Our last natural product paper on complex oligophenalenone dimers

Antimicrobial Oligophenalenone Dimers from the Soil Fungus Talaromyces stipitatus Yi Zang, Grégory Genta-Jouve, Alexandre E. Escargueil, Annette K. Larsen, Laura Guedon, Bastien Nay* and Soizic Prado* Journal of Natural Products 2017, ASAP, doi: 10.1021/acs.jnatprod.6b00458

Mehdi’s last paper on the total synthesis of the tiniest cytochalasin

First Total Synthesis, Structure Revision and Natural History of the Smallest Cytochalasin: (+) Periconiasin G Mehdi Zaghouani, Caroline Kunz, Laura Guédon, Florent Blanchard, Bastien Nay* Chemistry – A European Journal 2016, 22, 15257–15260, doi: 10.1002/chem.201603734 The total synthesis of the smallest cytochalasin isolated so far, periconiasin G, which bears a seven-membered ring in lieu of […]

First paper from Chinese collaboration

Alkaloids were isolated from the Chinese whole plant of Palhinhaea cernua f. sikkimensis.

Mehdi’s paper just released @NatProdRep

3-Acylated tetramic and tetronic acids as natural metal binders: myth or reality? M. Zaghouani and B. Nay: Natural Product Reports 2016, DOI: 10.1039/c5np00144g 3-Acylated tetramic and tetronic acids are characterized by a low pKa and are likely to be deprotonated under physiological conditions. In addition, their structure makes them excellent chelators of metallic cations. We […]

First paper 2016 !

Talaroketals A and B, unusual bis(oxaphenalenone) spiro and fused ketals from the soil Fungus talaromyces stipitatus ATCC 10500 Y. Zang, G. Genta-Jouve, P. Retailleau, S. Mann, B. Nay* and S. Prado* Organic and Biomolecular Chemistry 2016, 14, 2691-2697