Read our last paper on the oxygenation of resinic diterpenes, from Benjamin’s PhD work: Harnessing the potential diversity of resinic diterpenes through visible light-induced sensitized oxygenation coupled to Kornblum-DeLaMare and Hock reactions B. Laroche and B. Nay Organic Chemistry Frontiers 2017, in press, DOI: 10.1039/C7QO00633K Abstract: A biomimetic procedure for the late-stage functionalization of various […]

Just released A reactive eremophilane and its antibacterial 2(1H)‑naphthalenone rearrangement product, witnesses of a microbial chemical warfare S. Amand, M. Vallet, L. Guedon, G. Genta-Jouve, F. Wien, S. Mann, J. Dupont, S. Prado* and B. Nay* Organic Letters 2017, in press, doi: 10.1021/acs.orglett.7b01788 Abstract: Two sesquiterpenes, 4-epi-microsphaeropsisin (1) and a dihydrofurano-2(1H)-naphthalenone (variabilone, 2) which represents […]

Jonathan George was welcome on 12/7/2017 at LSO for a talk and passionating discussions on Biomimetic Synthesis of Natural Products. Among recent achievements: A unifying paradigm for naphthoquinone-based meroterpenoid (bio)synthesis Zachary D. Miles, Stefan Diethelm, Henry P. Pepper, David M. Huang, Jonathan H. George, Bradley S. Moore Nature Chem. 2017, ASAP Biomimetic Total Synthesis of (±)-Verrubenzospirolactone Hiu C. Lam, […]

The DISCO beamline at SOLEIL welcomes us for four days at Synchrotron SOLEIL from 6th to 9th July. This is a collaboration with Dr. Frank Wien (beamline team) and Dr. Séverine Zirah (Muséum National d’Histoire Naturelle), to study the structure of photoswitchable peptides. This is supported by SOLEIL.    

Dr Laurence Miesch (Laboratoire de Chimie Organique Synthétique – UMR7177, Strasbourg University) gave a talk today at LSO, on “Alkynyl ketones providing access to valuable building blocks.”

We attend the ICSN-UPSaclay Natural Products Symposium on 29th-30th June at Gif-sur-Yvette. Bastien is speaking on Friday morning about: Bio-inspired total synthesis… or not, a personal overview

We attend (and co-organize) the i-NPChem Workshop on Natural Product Biosynthesis on 28th June 2017 at Gif-sur-Yvette. Enjoying amazing and stimulating talks by the five speakers !

Benjamin Laroche received the YNSECT PhD Prize at the SCF Day of Ile-de-France Young Talents in Chemistry on 19th June 2017

Congratulations to Wei Zhang who got the SYNFACTS Posterprize at SFST7 (7th French Symposium on Total Synthesis), on 2nd June 2017, for her work on the total synthesis of functionalized diketopiperazines. Wei is a 2nd year PhD student.  

We will be at SFST7 at Orsay, 1-2 June 2017. Wei and Bastien attend. Wei will present her poster on her synthetic work: Biomimetic oxidative strategies and alternative route for the synthesis  natural products in the diketopiperazine series. Bastien co-organizes the symposium.